M.Sci. Biology, University of Bristol, 2018
Interests: synthetic biology, genetic circuits, proteolysis, m6A methylation
My research is part of the EU SynCrop project (Synthetic Circuits for Robust Orthogonal Production). It focuses on approaches that can be taken to mitigate the stress placed on host cells by synthetic genetic circuits. I will be looking at how proteolysis mechanisms can be used to degrade burdensome proteins produced by the circuits, as well as using high throughput approaches to investigate how m6A methylation in E. coli cells changes as a result of stress, and what its effects may be.
Improving the robustness of engineered bacteria to nutrient stress using programmed proteolysis
Szydlo K., Ignatova Z., Gorochowski T.E.
bioRxiv, 10.04.463040, 2021.